Your partner in science for end-to-end CRDMO solutions
Biophysical Facility at Jubilant Biosys provides highly sensitive, label-free and real-time assessment of bio molecular interaction through the Surface Plasmon Resonance (SPR) platform.
Our SPR services are carried out by our experienced scientific team that guides you through your project for various applications ranging from small molecule binding kinetics (reversible/ irreversible), fragments screening, protein aggregation, drug competition assay etc. . With having extensive knowledge in the drug discovery process, Jubilant Biosys offers tailored solutions to complex challenges that help in delivering successful results and achieve our mission.
The Structural Biology team offers, Surface Plasmon Resonance (SPR) services; using the Sartorius Pioneer FE and Octet systems) to facilitate FBDD (Fragment Based Drug Discovery) support to clients. An optical phenomenon, SPR, enables binding activity monitoring of any two unlabelled molecules in real-time. The generated signal is dependent on changes in the refractive index at the surface of a gold sensor chip, as an analyte flows in a microfluidic channel and binds to a ligand immobilized on the sensor chip. Consequently, over time, plotting the binding response vs time called sensorgram. The sensorgram aids in the calculation of binding parameters, such as KD, kon and koff. We have provided SPR support to programs studying protein-drug, RNA-drug, RNA-protein and protein-protein interactions.
