Physicochemical Properties

Physicochemical Properties

Physicochemical properties refer to the physical and chemical characteristics of a substance that define its behavior in various environments and applications. These properties include aspects such as solubility, pKa and partition coefficient, among others. Such properties play a pivotal role in supporting rational compound design by providing insight into the relationship between a molecule’s structure and its physical behavior within a system.

Jubilant Biosys offers comprehensive physicochemical property analysis as part of its drug discovery and development services. By utilizing advanced techniques and state-of-the-art equipment, Jubilant Biosys ensures accurate measurement and interpretation of these properties, aiding in the optimization of lead compounds. Their services include –

  • Distribution/Partition coefficient  (Shake flask/ chromatography method).
  • Aqueous solubility (Thermodynamic and Kinetic).
  • Solubility evaluation in bio-relevant media.
  • Chemical stability assessment.
  • pKa estimation.
  • Early formulation assessments.