Key In Vitro DMPK Services:
- Metabolic Stability: Assessing the rate at which a drug is metabolized in liver microsomes, hepatocytes, and other biological matrices.
- Enzyme Inhibition: Evaluating the potential of a compound to inhibit key drug-metabolizing enzymes such as CYP450s.
- Enzyme Induction: Determining if a compound induces the production of drug-metabolizing enzymes, affecting the metabolism of other drugs.
- Drug-Drug Interaction Studies: Predicting potential interactions with other medications that may be co-administered.
- Permeability and Transporter Studies: Evaluating how well a drug is absorbed and identifying the involvement of specific transporters.
Jubilant’s DMPK services are designed to support drug discovery and development programs by providing comprehensive in vitro DMPK studies. Here’s how Jubilant can assist:
Assay Technologies
- State-of-the-Art Facilities: Jubilant boasts advanced laboratories equipped with cutting-edge technology to conduct high-quality DMPK studies.
- Experienced Team: Our team of experts, with extensive experience in drug metabolism and pharmacokinetics, ensures that your compounds are thoroughly evaluated and characterized.
- Customized Solutions: We offer tailored services to meet the specific needs of your drug development program, providing you with relevant and actionable data.
- IVIVE: Jubilant integrates in vitro ADME data with in vivo pharmacokinetics to establish In vitro in vivo extrapolation. Also, integrates with in vivo pharmacology, toxicology, Metabolite characterization in multiple species and helps in comprehensive understanding of your compound’s behavior.
- Timely Delivery: We understand the importance of timely data in drug development. Our streamlined processes ensure that you receive accurate and reliable results promptly.
Partner with Jubilant for your in vitro DMPK needs and leverage our expertise to enhance the pharmacokinetic profiles of your drug candidates, accelerating their progress through the development pipeline.
