Jubilant Biosys Enters Into Oligonucleotides

Accelerate your oligonucleotide drug development with Jubilant Biosys, possessing specialized expertise in synthesizing oligonucleotides of varying lengths & incorporating a variety of linkers for bioconjugation to carbohydrates and antibodies.

Services

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Oligonucleotide Offerings

Jubilant Biosys offers advanced oligonucleotide synthesis services under stringent process controls. Backed by extensive technical expertise, we provide a wide range of chemistries and modifications customized to specific oligonucleotide sequences. Additionally, we deliver oligonucleotide conjugates for diverse applications and constructs.

Our capabilities include:

Oligonucleotide synthesis using automated oligonucleotide synthesizer
Custom DNA and RNA oligonucleotides synthesis
For various techniques such as PCR, antisense, siRNA, aptamer and CRISPR
Standard chemical modifications such as PS, 2′OMe, 2′F, 2′OMOE, LNA
Fluorescent oligonucleotides
Oligonucleotide conjugates (Small molecule, Carbohydrate, Lipid, Peptide)
Purification of oligonucleotides using anion-exchange and reversed-phase HPLC
Analysis of oligonucleotides through LCMS and NMR

Mermade 12 Automated Oligonucleotide Synthesizer

Oligonucleotide Platform

Monomer/linker/conjugate synthesis
Oligonucleotide LIbrary
Oligonucleotide Optimization
In vitro and in vivo efficacy/early tox screening, off-target
ADME and in vivo PK
Toxicology

Instrumentation Capabilities

Automated oligonucleotide synthesis capability (mg – gram scale)
12 column synthesizer
Solid phase synthesis using phosphoramidite approach