Our in vivo pharmacokinetics services include dose administration, sample collection, bioanalytical analysis, and data interpretation. We are committed to delivering high-quality data with fast turnaround times, enabling our clients to make informed decisions quickly and efficiently. We prioritize compliance with regulatory guidelines and ethical standards, ensuring that our pharmacokinetic studies advance your drug development projects and also uphold the highest standards of research integrity. Partner with us to leverage our expertise and accelerate your path to clinical success.
- At Jubilant Biosys we offer services to support non-GLP in vivo pharmacokinetics studies in preclinical rodent species, including study planning and sample analysis using state-of-the-art UPLC-MS/MS (Q-trap, triple quad).
- We offer administration routes and collection methods include dosing by oral (PO), intravenous (IV), intraperitoneal (IP), and subcutaneous (SC) as single agents or cassette dosing (up to 6 in 1)
- Capability to develop fit for purpose ADME and in vivo pharmacokinetic studies to scientifically support client requirements
- Jubilant Biosys is deeply committed to upholding the principles of the 3Rs – Replacement, Reduction, and Refinement – in all our scientific endeavours.
PK services offered by Jubilant
Rodents and non-rodents
- Rats (multiple strains)
- Mouse (multiple strains)
- Beagle dogs
- Monkeys (Rhesus)
- Mini-pigs
- Rabbits
- Dose proportionality studies
- Biliary, Urinary, fecal excretion studies
Tissue distribution studies in rodents
- Exposure kinetics in tissues of choice
- Cerebrospinal fluid collection
- BALF fluid collection
Dermal pharmacokinetics in rodents and non rodents
Mechanistic pharmacokinetics models in rats
- Bile duct cannulation
- Portal vein cannulation
- Carotid artery cannulation
- Jugular vein cannulation
- Femoral vein cannulation
- Expertise in developing quantitative LC-MS/MS methods for endogenous biomarkers in bio-fluids and tissue samples
